Hi Therian!
Ya you can prune it ^.^ Ficus are pretty tough. They lose their leaves from time to time, but that's cuz they're really sensitive to stuff. temperature change, wind, humidity, etc.
but ya, you can prune it
if you wana make a new
plant off of it, i'm not too sure about how you'd do it, but i've heard several ways to do it ^.^ Like, you can take a small knife, and cut part way into the branch ur cutting off at the point ur cutting it off at. Then you stuff some moss in there, and hold it there with a thing of cling wrap. Then you water it and wait a while. After a while, supposidly it'll grow roots in the moss and you can cut the branch off and root it from there ^.^
or you can cut it off and stick it in soil and hope for the best :p
good luck!!
~Phoebe